Annexin A2 Rabbit Recombinant mAb

生物描述

特异性

Annexin A2 Rabbit Recombinant mAb detects endogenous level of total Annexin A2.

背景

Annexin A2 (also called p36, annexin II, ANXA2, calpactin I, lipocortin II, chromobindin VIII, or placental anticoagulant protein IV), is expressed in some tumor cells, endothelial cells, macrophages, and mononuclear cells. ANXA2 expressed in the nucleus is cell-cycle-dependent. Intracellular ANXA2 has been reported to play roles in exocytosis, endocytosis, and membrane trafficking. Knockdown of ANXA2 inhibits cell division and proliferation. Furthermore, ANXA2 is essential for lipid raft formation and signal transduction through its interaction with CD44. It also mediates interferon gamma-induced inflammation via calcium-dependent regulation of protein tyrosine kinase 2. Extracellular ANXA2 plays a role in phagocytosis, fibrinolysis and anticoagulation, angiogenesis, and cell metastasis.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	38kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Chi-Yun Wang, et al. Disease Markers. 2014.

Application Data

WB

IHC