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Anti-mouse CD3ε-InVivo
目录号：A2104 批次号: A210408
克隆号：145-2C11
145-2C11单克隆抗体与小鼠CD3ε反应。小鼠CD3ε是一种20 kDa的跨膜细胞表面蛋白，属于免疫球蛋白超家族。145-2C11抗体已显示出在体外通过结合和刺激TCR诱导T淋巴细胞活化，增殖和凋亡的作用。据报道当在体内使用该抗体时，能产生T细胞活化，失能或死亡。
抗体信息
| 克隆号 | 145-2C11 |
|---|---|
| 免疫原 | Mouse BM10-37 cytotoxic T cells |
| 配制 | PBS buffer, pH 7.0 |
| 推荐同型对照 | Armenian Hamster IgG1 |
| 应用 | in vitro T cell stimulation/activation, IF, FCM, WB |
| 来源 | CHO |
| 小鼠病原体检测 | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| 储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
| 除菌 | 0.2 μM filtered |
| 纯度 | 99% |
| 蛋白浓度 | 6.79 mg/mL |
| 内毒素 | ＜1 EU/mg |
Anti-mouse CD3ε-InVivo在文献中得到引用
| Spatiotemporal Analysis of Mesenchymal Stem Cells Fate Determination by Inflammatory Niche Following Soft Tissue Injury at a Single-Cell Level [ Advanced Science, September 23, 2024, 11(43):e2310282] | PubMed: 39308190 |
| Near-infrared II fluorescence imaging of PD-L1 and VEGF for assessing and early prediction of “T+A” therapeutic responsiveness in hepatocellular carcinoma [ Materials Today Bio, June 1, 2026, 38:103228] | PubMed: 42211064 |
| Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity [ Experimental & Molecular Medicine, July 6, 2026, 1-15] | PubMed: 42409961 |
| Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity [ Experimental and Molecular Medicine, July 2026, nan] | PubMed: 42409961 |
| Adipocyte OX40L promotes adipose T cell activation and insulin resistance in obesity [ Experimental and Molecular Medicine, July 2026, Online ahead of print] | PubMed: 42409961 |
| Histone lactylation increases CXCL1 expression for neutrophil infiltration and immune escape in pancreatic cancer [ Nature Communications, February 9, 2026, 17(1):2526] | PubMed: 41663394 |
| Short-term starvation inhibits CD36 N-glycosylation and downregulates USP7 UFMylation to alleviate RBPJ-maintained T cell exhaustion in liver cancer [ Theranostics, April 28, 2025, 15(12):5931-5952] | PubMed: 40365281 |
| Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma [ Cell Communication and Signaling, 2026-02-02, 155] | PubMed: 41629991 |
| Disruption of FGL2 induces TFEB-dependent lysosomal degradation of PD-L1 and enhances the efficacy of anti-PD1 therapy in hepatocellular carcinoma [ Cell Communication and Signaling, 2026, Online ahead of print] | PubMed: 41629991 |
| Short-term starvation inhibits CD36 N-glycosylation and downregulates USP7 UFMylation to alleviate RBPJ-maintained T cell exhaustion in liver cancer [ Theranostics, 2025, 5931-5952] | PubMed: 40365281 |
禁止用于人体及治疗！