Anti-mouse IL-6-InVivo

目录号：A2118         批次号: A211811

       克隆号：MP5-20F3

打印

Anti-mouse IL-6-InVivo 单克隆抗体 (克隆号：MP5-20F3) 可与小鼠 IL-6 (interleukin-6) 发生反应。IL-6 是一种 21-28 kDa 的细胞因子，由多种细胞类型表达，包括 T 淋巴细胞、B淋巴细胞、单核细胞、成纤维细胞和内皮细胞。Anti-mouse IL-6-InVivo 已被证明可以中和天然或重组 IL-6 的生物活性。

抗体信息

克隆号 MP5-20F3
免疫原 Recombinant mouse IL-6
配制 PBS Buffer, PH 7.4
推荐同型对照 Rat IgG1, κ
应用 in vivo IL-6 neutralization
来源 CHO
小鼠病原体检测 all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus.
储存条件
(自收到货起)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
除菌 0.2 μM filtered
纯度 99%
蛋白浓度 4.70 mg/ml
内毒素 ＜1EU/mg

客户使用selleck产品的实验数据

Anti-mouse IL-6-InVivo在文献中得到引用

Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases [ Investigative Ophthalmology & Visual Science, September 2025, Vol.66, 44] PubMed: 40970669
Targeting RPE Senescence Via Suppressing IL-6/IL-6R Signaling for Treating Retinal Degenerative Diseases [ Investigative Ophthalmology & Visual Science, September 19, 2025, 66(12):44] PubMed: 40970669
Iron overload in CD11c+ myeloid cells exacerbates acetaminophen hepatotoxicity [ Communications Biology, October 21, 2025, 8(1):1488] PubMed: 41120657
Calcitonin receptor downregulation and exercise-conditioned blood enable systemic muscle stem cell proliferation [ Nature Communications, November 26, 2025, 16(1):10576] PubMed: 41298450
Oncolytic virus-induced IL-1β+ monocyte-IL-6+ CAF axis suppresses dendritic cell-mediated antitumor immunity in pancreatic cancer [ Journal for Immunotherapy of Cancer, November 1, 2025, 13(11):e013175] PubMed: 41253490
SR-717, a Non-Nucleotide STING Agonist, Displayed Anti-Radiation Activity in a IL-6 Dependent Manner [ The FASEB Journal, May 31, 2025, 39(11):e70644] PubMed: 40448435
Targeting CD177: A Novel Therapeutic Strategy for NLRP3-Associated Autoinflammatory Diseases [ International Journal of Molecular Sciences, March 20, 2026, 27(6):2841] PubMed: 41898699
Disruption of the Na+/K+-ATPase-purinergic P2X7 receptor complex in microglia promotes stress-induced anxiety [ Immunity, March 1, 2024, 57(3):495-512.e11] PubMed: 38395698
The increase of long noncoding RNA Fendrr in hepatocytes contributes to liver fibrosis by promoting IL-6 production [ The Journal of Biological Chemistry, June 1, 2024, 300(6):107376] PubMed: 38762176
Macrophage STING signaling promotes fibrosis in benign airway stenosis via an IL6-STAT3 pathway [ Nature Communications, January 3, 2025, 16(1):289] PubMed: 39753529

禁止用于人体及治疗！