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Anti-mouse PD-1 (CD279)-InVivo
目录号：A2122 批次号: A212271
克隆号：RMP1-14
Anti-mouse PD-1 (CD279)-InVivo(克隆号：RMP1-14)能够与小鼠PD-1（programmed death-1）也称为 CD279 发生反应。 PD-1 是由属于 Ig 超家族 CD28 家族的 Pdcd1 基因编码的 50-55 kDa 细胞表面受体。
抗体信息
| 克隆号 | RMP1-14 |
|---|---|
| 配制 | PBS Buffer, PH 7.4 |
| 推荐同型对照 | Rat IgG2a, κ |
| 应用 | in vivo blocking of PD-1/PD-L signaling |
| 来源 | CHO |
| 小鼠病原体检测 | all targets tested yielded Negative Results: Theiler’s Murine Encephalomyelitis Virus, Ectromelia (Mousepox) Virus, Hantavirus, Polyomavirus, Sendai Virus, Mycoplasma pulmonis, Pneumonia Virus of Mice, K Virus, Mouse Parvovirus, Mouse Hepatitis Virus, Mouse Norovirus, Mouse Minute Virus, Mouse Cytomegalovirus, Mouse Adenovirus, Lactate Dehydrogenase-Elevating Virus, Reovirus Panel, Lymphocytic Choriomeningitis Virus, Mouse Rotavirus. |
| 储存条件 (自收到货起) |
Store the undiluted solution at 4°C and avoid freeze-thaw cycle |
| 除菌 | 0.2 μM filtered |
| 纯度 | 99% |
| 蛋白浓度 | 8.67 mg/ml |
| 内毒素 | ＜1EU/mg |
客户使用selleck产品的实验数据
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Anti-mouse PD-1 (CD279)-InVivo在文献中得到引用
| Co-inhibition of PGF and VEGFA enhances the effectiveness of immunotherapy in bladder cancer [ International Journal of Medical Sciences, October 28, 2024, 21(15):2870-2882] | PubMed: 39628692 |
| EIF2B4 promotes hepatocellular carcinoma progression and immune evasion by driving STAT3 translation via a GEF-dependent mechanism [ Cellular Oncology, October 27, 2025, 48(6):1919-1933] | PubMed: 41144132 |
| Characteristics of tertiary lymphoid structures in prostate cancer and the impact of neoadjuvant therapy on their formation and maturation [ Frontiers in Immunology, November 4, 2025, 16:1663396] | PubMed: 41262256 |
| Yin Yang 1 Promotes Antiprogrammed Cell Death-1 Resistance in Hepatocellular Carcinoma through Polypeptide N-Acetylgalactosaminyltransferase 16-Mediated Glycosylation of Programmed Death Ligand-1 [ MedComm, November 26, 2025, 6(12):e70504] | PubMed: 41322030 |
| ZDHHC3-mediated SCAP S-acylation promotes cholesterol biosynthesis and tumor immune escape in hepatocellular carcinoma [ Cell Reports, November 1, 2024, 43(11):114962] | PubMed: 39522165 |
| Low-dose radiotherapy synergizes with PD-1 blockade to achieve durable survival in advanced NSCLC through antitumor neutrophil programming [ Signal Transduction and Targeted Therapy, May 7, 2026, 11(1):170] | PubMed: 42091852 |
| Betrixaban activates cGAS-STING to promote antitumor immunity without pathological inflammation [ EMBO Molecular Medicine, May 14, 2026, 18(6):2213-2235] | PubMed: 42135568 |
| CDK4/6 inhibitor abemaciclib combined with low-dose radiotherapy enhances the anti-tumor immune response to PD-1 blockade by inflaming the tumor microenvironment in Rb-deficient small cell lung cancer [ Translational Lung Cancer Research, May 1, 2024, 13(5):1032-1046] | PubMed: 38854937 |
| Oncolytic virus M1 reinvigorates CD8+ T-cell immunity against glioblastoma through B-cell-dependent antigen cross-presentation in the spleen [ Cellular and Molecular Immunology, March 4, 2026, 23(4):349-366] | PubMed: 41781696 |
| PD-1 blockade plus tyrosine kinase inhibitor remodels the tumor microenvironment in advanced renal cell carcinoma [ Nature Communications, March 31, 2026, 17(1):4626] | PubMed: 41916996 |
禁止用于人体及治疗！