Apg12 Rabbit Recombinant mAb

生物描述

特异性

Apg12 Rabbit Recombinant mAb detects endogenous level of total Apg12.

背景

The Apg12 system is one of the ubiquitin-like protein conjugation systems conserved in eukaryotes. It is highly conserved in mammals. Apg12 is conjugated to Apg5, which is catalyzed by Apg7 and Apg10. The covalent attachment of Atg12 to ATG5 through a ubiquitin-like conjugation system is required for autophagy. Atg12 is found to be involved in apoptosis. This protein promotes apoptosis through an interaction with anti-apoptotic members of the Bcl-2 family.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human
MW (kDa)	20,55kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Mizushima N, et al. Int J Biochem Cell Biol. 2003, 35(5):553-61. [2] Strausberg RL, et al. Proc Natl Acad Sci U S A. 2002, 99(26):16899-903.

Application Data

WB

IHC