Aromatase Rabbit Recombinant mAb

生物描述

特异性

Aromatase Rabbit Recombinant mAb detects endogenous level of total Aromatase.

背景

Aromatase is the key enzyme for estrogen biosynthesis. It is localized in the endoplasmic reticulum of estrogen-producing cells. Aromatase enzyme complex is comprised of two polypeptides. The first of these is a specific cytochrome P450 (P450), namely aromatase cytochrome P450 (P450arom) (the product of the CYP19 gene). The second is a flavoprotein, NADPH-cytochrome P450 reductase and is ubiquitously distributed in most cells. Cell-specific expression of P450arom determines the presence or absence of aromatase activity.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Rat
MW (kDa)	53kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Bulun SE, et al. Pharmacol Rev. 2005, 57(3):359-83.

Application Data

WB

IHC