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目录号:A2004 批次号: A200407
Atezolizumab (anti-PD-L1)是人源、IgG1单克隆抗体,阻止PD-L1与PD-1和B7.1的相互作用,但不影响PD-L2与PD-1的相互作用;MW:145 KD。
CAS号 | 1380723-44-3 |
---|---|
配制 | PBS buffer, pH 7.2 |
推荐同型对照 | Human IgG1 |
来源 | CHO cells |
储存条件 (自收到货起) |
Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles |
纯度 | 99% |
蛋白浓度 | 6.2mg/ml |
内毒素 | <1EU/mg |
[ Int Immunopharmacol, 2024, ] | PubMed: 38442580 |
Pivotal role of myeloid-derived suppressor cells in infection-related tumor growth [ Cancer Med, 2024, 13(4):e6917] | PubMed: 38457241 |
Acquired resistance to CDK4/6 inhibition is associated with dysregulation of multiple pathways including cyclin D-CDK4/6-RB, EGFR/HER, AKT/mTOR and IFN [ Research Square, 2024, 10.21203/rs.3.rs-3782509/v1] | PubMed: none |
Engineering high-affinity dual targeting cellular nanovesicles for optimised cancer immunotherapy [ J Extracell Vesicles, 2023, 12(11):e12379] | PubMed: 37974395 |
YAP1 expression is associated with survival and immunosuppression in small cell lung cancer [ Cell Death Dis, 2023, 14(9):636] | PubMed: 37752152 |
YAP1 expression is associated with survival and immunosuppression in small cell lung cancer [ Cell Death Dis, 2023, 14(9):636] | PubMed: 37752152 |
Synergistically Enhancing Immunotherapy Efficacy in Glioblastoma with Gold-Core Silica-Shell Nanoparticles and Radiation [ Int J Nanomedicine, 2023, 18:7677-7693] | PubMed: 38111846 |
Analysis of the mechanisms regulating soluble PD-1 production and function in human NK cells [ Front Immunol, 2023, 14:1229341] | PubMed: 37638041 |
ISG15 targets glycosylated PD-L1 and promotes its degradation to enhance antitumor immune effects in lung adenocarcinoma [ J Transl Med, 2023, 21(1):341] | PubMed: 37217923 |
Self-assembled albumin nanoparticles induce pyroptosis for photodynamic/photothermal/immuno synergistic therapies in triple-negative breast cancer [ Front Immunol, 2023, 14:1173487] | PubMed: 37342347 |
禁止用于人体及治疗!