ATG9A Rabbit Recombinant mAb

目录号：A5123

生物描述

特异性	ATG9A Rabbit Recombinant mAb detects endogenous level of total ATG9A.
背景	Autophagy is an intracellular degradation pathway conserved in eukaryotes. Among core autophagy-related (Atg) proteins, mammalian Atg9A is the sole multi-spanning transmembrane protein, and both of its N- and C-terminal domains are exposed to the cytoplasm. Atg9A travels through the trans-Golgi network (TGN) and the endosomal system under nutrient-rich conditions, and transiently localizes to the autophagosome upon autophagy induction. Atg9a is an essential requirement for autophagy.

特异性

ATG9A Rabbit Recombinant mAb detects endogenous level of total ATG9A.

背景

Autophagy is an intracellular degradation pathway conserved in eukaryotes. Among core autophagy-related (Atg) proteins, mammalian Atg9A is the sole multi-spanning transmembrane protein, and both of its N- and C-terminal domains are exposed to the cytoplasm. Atg9A travels through the trans-Golgi network (TGN) and the endosomal system under nutrient-rich conditions, and transiently localizes to the autophagosome upon autophagy induction. Atg9a is an essential requirement for autophagy.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

1:1000

反应性

Human Mouse Rat

MW (kDa)

94kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Imai K, et al. J Cell Sci. 2016, 129(20):3781-3791.
[2] Saitoh T, et al. Proc Natl Acad Sci U S A. 2009, 106(49):20842-6.

Application Data

Validated by Selleck