Berberine

目录号：S9046 批次号：S904603

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化学数据

化学结构式 别名 Umbellatine 储存条件
(自收到货起)		 3年 -20°C 粉状
化学式

C20H18NO4
分子量 336.36 CAS号 2086-83-1
Solubility (25°C)* 体外 DMSO 7 mg/mL (20.81 mM)
Ethanol 6 mg/mL (17.83 mM)
Water Insoluble
体内（现配现用）
澄清溶液
5%DMSO Corn oil
0.37mg/ml (1.10mM) 以 1 mL 工作液为例，取50μL7.4mg/ml的澄清DMSO储备液加到950μL玉米油中，混合均匀。工作液请现配现用！
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述 Berberine (Umbellatine), an alkaloid isolated from Rhizoma coptidis, has broad applications, particularly as an antibacterial agent in the clinic.

推荐的实验操作(此推荐来自于公开的文献所以Selleck并不保证其有效性)

Berberine在文献中得到引用

Berberine ameliorates dextran sulfate sodium -induced colitis through tuft cells and bitter taste signalling [ BMC Biol, 2024, 22(1):280] PubMed: 39617924
The improvement of modified Si-Miao granule on hepatic insulin resistance and glycogen synthesis in type 2 diabetes mellitus involves the inhibition of TNF-α/JNK1/IRS-2 pathway: network pharmacology, molecular docking, and experimental validation [ Chin Med, 2024, 19(1):128.] PubMed: 39285464
System analysis of Huang-Lian-Jie-Du-Tang and their key active ingredients for overcoming CML resistance by suppression of leukemia stem cells [ Phytomedicine, 2023, 117:154918] PubMed: 37329755
Nao Tan Qing ameliorates Alzheimer's disease-like pathology by regulating glycolipid metabolism and neuroinflammation: A network pharmacology analysis and biological validation [ Pharmacol Res, 2022, 185:106489] PubMed: 36228869
Vagus nerve stimulated by microbiota-derived hydrogen sulfide mediates the regulation of berberine on microglia in transient middle cerebral artery occlusion rats [ Phytother Res, 2022, 10.1002/ptr.7490] PubMed: 35583808
Berberine Sensitizes Human Hepatoma Cells to Regorafenib via Modulating Expression of Circular RNAs [ Front Pharmacol, 2021, 12:632201] PubMed: 34220494
Quantitative Proteomics Analysis of Berberine-Treated Colon Cancer Cells Reveals Potential Therapy Targets [ Biology (Basel), 2021, 10(3)250] PubMed: 33806918
Berberine exerts neuroprotective activities against cerebral ischemia/reperfusion injury through up-regulating PPAR-γ to suppress NF-κB-mediated pyroptosis [ Brain Res Bull, 2021, 177:22-30] PubMed: 34517069
Sensitivity of pancreatic cancer cells to chemotherapeutic drugs, signal transduction inhibitors and nutraceuticals can be regulated by WT-TP53 [ Adv Biol Regul, 2021, S2212-4926(20)30091-9] PubMed: 33451973
Suppression effect of plant-derived berberine on cyprinid herpesvirus 2 proliferation and its pharmacokinetics in Crucian carp (Carassius auratus gibelio) [ Antiviral Res, 2020, 186:105000] PubMed: 33359191

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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