β-Nicotinamide Mononucleotide

目录号：S5259 批次号：S525908

化学数据

	别名	β-NM, NMN	储存条件 (自收到货起)	3年 -20°C 粉状
	化学式	C₁₁H₁₅N₂O₈P
	分子量	334.22	CAS号	1094-61-7
Solubility (25°C)*	体外	Water	67 mg/mL (200.46 mM)
		DMSO	Insoluble
		Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

生物活性

产品描述	Nicotinamide mononucleotide (β-NM, NMN)是NAD+的关键前体之一，也是NAMPT反应的产物，通过烟酰胺单核苷酸腺苷酸转移酶转化为NAD+。

参考文献

β-Nicotinamide Mononucleotide在文献中得到引用

Mitochondrial-cytochrome c oxidase II promotes glutaminolysis to sustain tumor cell survival upon glucose deprivation [ Nat Commun, 2025, 16(1):212]	PubMed: 39747079
Histidine triad nucleotide-binding protein 2 attenuates doxorubicin-induced cardiotoxicity through restoring lysosomal function and promoting autophagy in mice [ MedComm (2020), 2025, 6(3):e70075]	PubMed: 39968501
Inactivation of the SLC25A1 gene during embryogenesis induces a unique senescence program controlled by p53 [ Cell Death Differ, 2024, 10.1038/s41418-024-01428-w]	PubMed: 39733217
DePARylation is critical for S phase progression and cell survival [ Elife, 2024, 12RP89303]	PubMed: 38578205
SIRT1 stabilizes β-TrCP1 to inhibit Snail1 expression in maintaining intestinal epithelial integrity to alleviate colitis [ Cell Mol Gastroenterol Hepatol, 2024, S2352-345X(24)00108-5]	PubMed: 38729522
β-Nicotinamide Mononucleotide Reduces Oxidative Stress and Improves Steroidogenesis in Granulosa Cells Associated with Sheep Prolificacy via Activating AMPK Pathway [ Antioxidants (Basel), 2024, 14(1)34]	PubMed: 39857368
NAD+ regulates nucleotide metabolism and genomic DNA replication [ Nat Cell Biol, 2023, 10.1038/s41556-023-01280-z]	PubMed: 37957325
ABCA7 deficiency causes neuronal dysregulation by altering mitochondrial lipid metabolism [ Mol Psychiatry, 2023, 10.1038/s41380-023-02372-w]	PubMed: 38135757
Temperature-sensitive hydrogel dressing loaded with nicotinamide mononucleotide accelerating wound healing in diabetic mice [ Biomed Pharmacother, 2023, 10.1016/j.biopha.2023.115431]	PubMed: 37688988
β-nicotinamide mononucleotide rescues the quality of aged oocyte and improves subsequent embryo development in pigs [ PLoS One, 2023, 18(10):e0291640]	PubMed: 37796824

特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品，在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同，大多数建议储存在-20°C，抑制剂属于化学试剂，可在常温下运输储存两周左右。即使如此，我们保证产品的出货量将保持产品质量的条件下，一般都会放入冰袋。望阁下收到产品后，请按照产品数据表建议适当存储。

如果需要长期保存，请于零下二十度低温保存。禁止用于人体及治疗！

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