Bevacizumab (anti-VEGF)

目录号：A2006         批次号: A200605

打印

Bevacizumab (anti-VEGF, Avastin) 是一种人源化的anti-VEGF单克隆抗体，是VEGF的抑制剂。可与所有人源VEGF-A亚型（和具有生物活性的蛋白水解片段）结合、中和。MW:149 KD。

抗体信息

CAS号 216974-75-3
配制 PBS buffer, pH 7.2
推荐同型对照 Human IgG1
来源 CHO cells
储存条件
(自收到货起)		 Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles
纯度 98.78%
蛋白浓度 5 mg/ml
内毒素 <1 EU/mg

客户使用selleck产品的实验数据

数据来源于[Data independently produced by , , Cancer Lett, 2018, 439:78-90]

VEGFA expression in the indicated cells treated with or without bevacizumab or transfected with VEGFA or shVEGFA.

Bevacizumab (anti-VEGF)在文献中得到引用

Leukemic stem cells activate lineage inappropriate signalling pathways to promote their growth [ Nat Commun, 2024, 15(1):1359] PubMed: 38355578
Interferon-regulatory factor-1 boosts bevacizumab cardiotoxicity by the vascular endothelial growth factor A/14-3-3γ axis [ ESC Heart Fail, 2024, 10.1002/ehf2.14640] PubMed: 38234115
EDIL3 as an Angiogenic Target of Immune Exclusion Following Checkpoint Blockade [ Cancer Immunol Res, 2023, 11(11):1493-1507] PubMed: 37728484
L1CAM promotes vasculogenic mimicry formation by miR-143-3p-induced expression of hexokinase 2 in glioma [ Mol Oncol, 2023, none] PubMed: 36708044
In vitro vascularized immunocompetent patient-derived model to test cancer therapies [ iScience, 2023, 26(10):108094] PubMed: 37860774
Development of an Anti-Idiotype Aptamer-Based Electrochemical Sensor for a Humanized Therapeutic Antibody Monitoring [ Int J Mol Sci, 2023, 24(6)5277] PubMed: 36982354
Development of an Anti-Idiotype Aptamer-Based Electrochemical Sensor for a Humanized Therapeutic Antibody Monitoring [ Int J Mol Sci, 2023, 24(6)5277] PubMed: 36982354
Subcutaneous transplantation of human embryonic stem cells-derived pituitary organoids [ Front Endocrinol (Lausanne), 2023, 14:1130465] PubMed: 36936140
Angiopoietin-2 and the Vascular Endothelial Growth Factor Promote Migration and Invasion in Hepatocellular Carcinoma- and Intrahepatic Cholangiocarcinoma-Derived Spheroids [ Biomedicines, 2023, 12(1)87] PubMed: 38255193
Immune suppressive signaling regulated by latent transforming growth factor beta binding protein 1 promotes metastasis in cervical cancer [ Braz J Med Biol Res, 2023, 55:e12206] PubMed: 36629522

禁止用于人体及治疗！