Biotin Human CD132 common γ chain Antibody [TUGh4]

目录号:H2910

打印

生物描述

特异性
背景 CD132是一种64-70 kDa的I型跨膜糖蛋白,属于免疫球蛋白超家族,也称为共同γ链(γc)或IL-2受体γ亚基。它广泛表达于T淋巴细胞、B淋巴细胞、NK细胞、单核细胞和粒细胞。CD132是IL-2、IL-4、IL-7、IL-9、IL-15和IL-21细胞因子受体的必需组成部分。配体结合诱导酪氨酸磷酸化,并通过JAK/STAT通路启动信号传导。CD132突变导致X连锁重症联合免疫缺陷(XSCID)。

使用信息

抗体应用 FCM 推荐用量 5 uL/million cells in 100 µL volume
反应性 Human, African Green, Cynomolgus, Rhesus
抗体类型 Rat MW 64-70 kDa
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide and 0.2% (w/v) BSA
储存条件
(自收到货起)
Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining of normal human peripheral blood mononuclear cells (PBMCs) using Biotin Human CD132 common γ chain Antibody [TUGh4] (Product No.: H2910) and SA-AF647, FITC CD4 Antibody. Analyzed data are derived from live lymphocytes.