Biotin mouse Dectin-1 Antibody [2A11]

目录号:G2430

打印

生物描述

特异性
背景 Dectin-1,也称为CLEC7A,是一种43 kD的II型跨膜蛋白。Dectin-1的胞外部分包含一个C型凝集素结构域,其胞质尾部有一个基于免疫受体酪氨酸的活化基序。Dectin-1结合β-1,3-连接和β-1,6-连接的葡聚糖(在真菌和酵母细胞壁中含量丰富),介导吞噬作用,并诱导细胞因子产生和氧化爆发。它还参与TLR2介导的NF-κB活化。Dectin-1由巨噬细胞、中性粒细胞、树突状细胞和朗格汉斯细胞表达。

使用信息

抗体应用 FCM, IHC 推荐用量 0.2 μg ( 0.4 μL) / million cells in 100 µL volume
反应性 Mouse
抗体类型 Rat MW
储存液配方 Phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide
储存条件
(自收到货起)
Store at 4°C in the dark to avoid freeze-thaw cycles

Application Data

FCM

Validated by Selleck

  • Staining of bone marrow cells from C57BL/6 mice using Biotin mouse Dectin-1 Antibody [2A11] (Selleck Cat.: G2430) and SA-AF647, and FITC LY-6G Antibody (green, with red blank control). Analyzed data are derived from total live cells.