目录号：A5797

打印

生物描述

特异性

BIRC2 Rabbit Recombinant mAb detects endogenous levels of total BIRC2.
背景

BIRC2 (also called cIap1) belongs to the IAP family of anti-apoptotic proteins. Besides the potent anti-apoptotic property, BIRC2 can also act as an E3 ligase to ubiquitylate and regulate target proteins, thereby participating in the regulation of multiple cellular functions. BIRC2 is essential for maintaining endothelial cell survival and blood vessel homeostasis during vascular development. It is a a repressor of the noncanonical NF-κB pathway and a potent negative regulator of LTR-dependent HIV-1 transcription.

使用信息

抗体应用 WB,ELISA,ELISA
稀释比例
WB
1:1000
反应性 Human
MW (kDa) 70kDa
抗体类型
储存液配方 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件
(自收到货起)		 Store at –20°C.

Application Data

WB

Validated by Selleck