生物描述

特异性

C4 Rabbit Recombinant mAb detects endogenous levels of total C4.

背景

The complement system, exists in tissues and serum, is a part of immune system that helps or complements the ability of antibodies and phagocytic cells to clear pathogens from the organism. Complement component 4 (C4), a protein involved in complement system, takes part in multiple aspects of the immune system. C4 takes part in T cells differentiation to Treg cells via DCs. As with other components of the complement system, C4 is expressed primarily in the liver and in macrophages, and its expression is induced in response to acute inflammation or tissue injury. High plasma C4 concentration is primarily due to liver synthesis, while macrophages deliver complement locally.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human
MW (kDa)	193kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Hong-Bin Cheng, et al. Cell & Bioscience. 2015, 5:73. [2] Banerjee A, et al. J Virol. 2011, 85(9):4157-66.

Application Data

WB

IF