Calponin Rabbit Recombinant mAb Datasheet

生物描述

特异性	Calponin Rabbit Recombinant mAb detects endogenous level of total Calponin.
背景	Calponin is an actin filament-associated regulatory protein expressed in smooth muscle and multiple types of non-muscle cells. calponin binds actin and cross-links actin filaments. It also binds or interacts with many other cytoskeleton and related proteins, including tropomyosin, myosin, tubulin, desmin, gelsolin, Ca2+-calmodulin, Ca2+-S100 and phospholipids. Calponin was also reported to interact with caldesmon, and α-actinin. Besides modulating the function of smooth muscle myofilaments and contractility, calponin also regulates the actin cytoskeleton of non-muscle cells to effect on many cellular activities, such as proliferation, adhesion, migration, differentiation, phagocytosis and fusion.

特异性

Calponin Rabbit Recombinant mAb detects endogenous level of total Calponin.

背景

Calponin is an actin filament-associated regulatory protein expressed in smooth muscle and multiple types of non-muscle cells. calponin binds actin and cross-links actin filaments. It also binds or interacts with many other cytoskeleton and related proteins, including tropomyosin, myosin, tubulin, desmin, gelsolin, Ca2+-calmodulin, Ca2+-S100 and phospholipids. Calponin was also reported to interact with caldesmon, and α-actinin. Besides modulating the function of smooth muscle myofilaments and contractility, calponin also regulates the actin cytoskeleton of non-muscle cells to effect on many cellular activities, such as proliferation, adhesion, migration, differentiation, phagocytosis and fusion.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:500

反应性

Human Mouse Rat Dog Pig

MW (kDa)

34kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Liu R, et al. Gene. 2016, 585(1):143-153.

Application Data

WB

Validated by Selleck