CD52 Rabbit Recombinant mAb Datasheet

生物描述

特异性	CD52 Rabbit Recombinant mAb detects endogenous level of total CD52.
背景	CD52 is a small molecule that is located on the cell surface of some inflammatory cells (mainly lymphocytes, natural killer cells, and monocytes). CD52 is not expressed on hematopoietic progenitors, erythrocytes, or platelets. Binding to the CD52 antigen of inflammatory cells causes complement- mediated cell lysis. Furthermore, it is found within the male genital tract and is present on the surface of mature sperm cells. CD52 plays complicated roles on T-cell activation via multiple pathways. It can modulate T-cell activation either by its intracellular signal pathways or by the interaction of soluble CD52 and Siglec-10 expressing on T cells. CD52 acts as costimulatory molecules to activate effectors and regulatory T cells.

特异性

CD52 Rabbit Recombinant mAb detects endogenous level of total CD52.

背景

CD52 is a small molecule that is located on the cell surface of some inflammatory cells (mainly lymphocytes, natural killer cells, and monocytes). CD52 is not expressed on hematopoietic progenitors, erythrocytes, or platelets. Binding to the CD52 antigen of inflammatory cells causes complement- mediated cell lysis. Furthermore, it is found within the male genital tract and is present on the surface of mature sperm cells. CD52 plays complicated roles on T-cell activation via multiple pathways. It can modulate T-cell activation either by its intracellular signal pathways or by the interaction of soluble CD52 and Siglec-10 expressing on T cells. CD52 acts as costimulatory molecules to activate effectors and regulatory T cells.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Mouse

MW (kDa)

8kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck