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特异性 | CDC40 Rabbit Recombinant mAb detects endogenous level of total CDC40. |
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背景 | CDC40, also known as EHB3, PRP17, and PRPF17, is found in the spliceosome and contains seven WD repeats, which function in protein-protein interactions. CDC40 controls cell cycle through splicing of intron-containing pre-mRNAs that encode proteins important for cell cycle progression. The CDC40 wild type exhibits a delayed G1/S transition, progresses slowly through S-phase, and arrests at a restrictive temperature in the G2 phase. CDC40 is needed for the maintenance or establishment of the mitotic spindle. |
抗体应用 | WB ,ELISA,ELISA | ||
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稀释比例 |
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反应性 | Human Mouse Rat | ||
MW (kDa) | 74kDa | ||
抗体类型 | Rabbit | ||
储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||
储存条件 (自收到货起) |
Store at –20°C. |
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WB
Validated by Selleck