Claudin 1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Claudin 1 Rabbit Recombinant mAb detects endogenous level of total Claudin 1.
背景	Claudins are tetraspan transmembrane proteins of tight junctions. They determine the barrier properties of this type of cell–cell contact existing between the plasma membranes of two neighbouring cells, such as occurring in endothelia or epithelia. Sequence analysis of claudins has led to differentiation into two groups, designated as classic claudins (1–10, 14, 15, 17, 19) and non-classic claudins (11–13, 16, 18, 20–24), according to their degree of sequence similarity. The claudins are expressed in a tissue specific combination resulting in tissue specific barrier characteristics. Claudin-1 is most highly expressed in liver, but is also found in several other epithelial tissues. Claudin-1 is a critical HCV entry cofactor.

特异性

Claudin 1 Rabbit Recombinant mAb detects endogenous level of total Claudin 1.

背景

Claudins are tetraspan transmembrane proteins of tight junctions. They determine the barrier properties of this type of cell–cell contact existing between the plasma membranes of two neighbouring cells, such as occurring in endothelia or epithelia. Sequence analysis of claudins has led to differentiation into two groups, designated as classic claudins (1–10, 14, 15, 17, 19) and non-classic claudins (11–13, 16, 18, 20–24), according to their degree of sequence similarity. The claudins are expressed in a tissue specific combination resulting in tissue specific barrier characteristics. Claudin-1 is most highly expressed in liver, but is also found in several other epithelial tissues. Claudin-1 is a critical HCV entry cofactor.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

19kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck