CRMP2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	CRMP2 Rabbit Recombinant mAb detects endogenous level of total CRMP2.
背景	Collapsin response mediator protein-2 (DPYSL2 or CRMP2) is a multifunctional adaptor protein within the central nervous system. In neurons, CRMP2 normally is concentrated within the distal portions of neurites, in synapses and in growth cones. In the developing brain or cell cultures, CRMP2 performs structural and regulatory functions related to cytoskeletal dynamics, vesicle trafficking and synaptic physiology. CRMP2 has been associated with several neuropathologic or psychiatric conditions including Alzheimer's disease (AD) and schizophrenia, either at the level of genetic polymorphisms; protein expression; post-translational modifications; or protein/protein interaction.

特异性

CRMP2 Rabbit Recombinant mAb detects endogenous level of total CRMP2.

背景

Collapsin response mediator protein-2 (DPYSL2 or CRMP2) is a multifunctional adaptor protein within the central nervous system. In neurons, CRMP2 normally is concentrated within the distal portions of neurites, in synapses and in growth cones. In the developing brain or cell cultures, CRMP2 performs structural and regulatory functions related to cytoskeletal dynamics, vesicle trafficking and synaptic physiology. CRMP2 has been associated with several neuropathologic or psychiatric conditions including Alzheimer's disease (AD) and schizophrenia, either at the level of genetic polymorphisms; protein expression; post-translational modifications; or protein/protein interaction.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

62kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Hensley K, et al. Mol Neurobiol. 2011, 43(3):180-91.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck