Ctip2 Rabbit Recombinant mAb

目录号：A5452

生物描述

特异性	Ctip2 Rabbit Recombinant mAb detects endogenous level of total Ctip2.
背景	COUP-TF-interacting protein 2 (Ctip2; also known as Bcl11b), a C2H2 zinc finger transcription factor, is expressed predominantly in central nervous system, thymocytes, skin, olfactory epithelium and in oral and gut epithelia. It is involved in development, T lineage commitment, cancer, and HIV-1 gene silencing. Ctip2 is a direct inhibitor of Cdk9 enzymatic activity and thus contributes to the inhibition of P-TEFb function.

特异性

Ctip2 Rabbit Recombinant mAb detects endogenous level of total Ctip2.

背景

COUP-TF-interacting protein 2 (Ctip2; also known as Bcl11b), a C2H2 zinc finger transcription factor, is expressed predominantly in central nervous system, thymocytes, skin, olfactory epithelium and in oral and gut epithelia. It is involved in development, T lineage commitment, cancer, and HIV-1 gene silencing. Ctip2 is a direct inhibitor of Cdk9 enzymatic activity and thus contributes to the inhibition of P-TEFb function.

使用信息

抗体应用

WB,ELISA

稀释比例

1:1000

反应性

Human

MW (kDa)

140kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Zhang LJ, et al. J Cell Sci. 2012, 125(Pt 23):5733-44.
[2] Cherrier T, et al. Proc Natl Acad Sci U S A. 2013, 110(31):12655-60.

Application Data

Validated by Selleck