CXCR3 Rabbit Recombinant mAb

生物描述

特异性

CXCR3 Rabbit Recombinant mAb detects endogenous level of total CXCR3.

背景

CXCR3 is a chemokine receptor that is highly expressed on effector T cells and plays an important role in T cell trafficking and function. CXCR3 is absent on naïve T cells, but is rapidly upregulated following dendritic cell (DC)-induced T-cell activation. CXCR3 is activated by three interferon-inducible ligands CXCL9 (MIG), CXCL10 (IP-10) and CXCL11 (I-TAC). CXCR3 plays a role in the migration of T cells in the microenvironment of the peripheral tissue and lymphoid compartment, facilitating the interaction of T cells with antigen presenting cells leading to the generation of effector and memory cells.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human
MW (kDa)	41kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Groom JR, et al. Exp Cell Res. 2011, 317(5):620-31. [2] Groom JR, et al. Immunol Cell Biol. 2011, 89(2):207-15.

Application Data

WB

IHC