Cytokeratin 15 Rabbit Recombinant mAb

生物描述

特异性

Cytokeratin 15 Rabbit Recombinant mAb detects endogenous level of total Cytokeratin 15.

背景

Keratins are structurally related proteins that form intermediate filaments (IFs) in epithelial cells. Together with actin microfilaments and microtubules intermediate filaments build the cytoskeleton of eukaryotic cells. Cytokeratin 15 is an intermediate filament (IF) type I proteins. It is expressed in the basal keratinocytes of all stratified epithelia. Although it is a minor component of the cytoskeleton with a variable expression pattern, nonetheless its expression has been reported as a stem cell marker in the bulge of hair follicles. Conversely, suprabasal expression of K15 has also been reported in both normal and diseased tissues, which is inconsistent with its role as a stem cell marker.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Mouse
MW (kDa)	45kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Badock V, et al. Cell Death Differ. 2001, 8(3):308-15. [2] Amrita Bose, et al. Int J Mol Sci. 2013, 14(10): 19385–19398.

Application Data

WB

IHC