Cytokeratin 16 Rabbit Recombinant mAb

生物描述

特异性

Cytokeratin 16 Rabbit Recombinant mAb detects endogenous level of total Cytokeratin 16.

背景

keratin 16 (Krt16), a type I intermediate filament cytoskeletal protein, is an integral and functionally important component of a genetic network regulating danger signals, innate immunity, and barrier function in skin epidermis. Krt16 is a direct target for EGFR and Erk1/2-mediated signaling and also a direct target for signaling mediated by the Nrf2 transcription factor, a master regulator of ROS levels and the oxidative stress response in skin.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human
MW (kDa)	51kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Juliane C. Lessard, et al. Proc Natl Acad Sci U S A. 2013, 110(48): 19537–19542.

Application Data

WB

IHC