Datasheet

生物描述

特异性	Dopamine Receptor D3 Rabbit Recombinant mAb detects endogenous levels of total Dopamine Receptor D3
背景	Dopamine is an essential neurotransmitter in the central nervous system and exerts its effects through activation of five distinct dopamine receptor subtypes that belong to the G protein-coupled receptor (GPCR) superfamily. The receptors have been classified into two subfamilies, D1-like and D2-like, on the basis of their sequence and pharmacological similarities. The D1-like receptors (D1R and D5R) couple to stimulatory G-protein alpha subunits (Gs/olf), activating adenyl cyclase, whereas D2-like receptors (D2R, D3R and D4R) couple to inhibitory G-protein alpha subunits (Gi/o), inhibiting adenyl cyclase.

特异性

Dopamine Receptor D3 Rabbit Recombinant mAb detects endogenous levels of total Dopamine Receptor D3

背景

Dopamine is an essential neurotransmitter in the central nervous system and exerts its effects through activation of five distinct dopamine receptor subtypes that belong to the G protein-coupled receptor (GPCR) superfamily. The receptors have been classified into two subfamilies, D1-like and D2-like, on the basis of their sequence and pharmacological similarities. The D1-like receptors (D1R and D5R) couple to stimulatory G-protein alpha subunits (Gs/olf), activating adenyl cyclase, whereas D2-like receptors (D2R, D3R and D4R) couple to inhibitory G-protein alpha subunits (Gi/o), inhibiting adenyl cyclase.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

44kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Chien EY, et al. Science. 2010,19;330(6007):1091-5.

Application Data

WB

Validated by Selleck