eIF5A Rabbit Recombinant mAb Datasheet

生物描述

特异性	eIF5A Rabbit Recombinant mAb detects endogenous level of total eIF5A.
背景	Eukaryotic translation initiation factor (eIF) 5A is a small, essential protein that is ubiquitous and highly conserved among eukaryotes and archaea. eIF5A is a eukaryotic translation initiation factor that is involved in protein translation in all eukaryotic organisms. It is implicated in the regulation of p53 expression and thereby p53-dependent apoptosis through interactions with syntenin, independent of its influences on protein translation. Other proposed functions of eIF5A include serving as a cofactor of HIV-1 REV to regulate nuclear export and RNA turnover as well as maintaining cell wall integrity and actin polarity.

特异性

eIF5A Rabbit Recombinant mAb detects endogenous level of total eIF5A.

背景

Eukaryotic translation initiation factor (eIF) 5A is a small, essential protein that is ubiquitous and highly conserved among eukaryotes and archaea. eIF5A is a eukaryotic translation initiation factor that is involved in protein translation in all eukaryotic organisms. It is implicated in the regulation of p53 expression and thereby p53-dependent apoptosis through interactions with syntenin, independent of its influences on protein translation. Other proposed functions of eIF5A include serving as a cofactor of HIV-1 REV to regulate nuclear export and RNA turnover as well as maintaining cell wall integrity and actin polarity.

使用信息

抗体应用

WB, IHC,ELISA,ELISA

稀释比例

WB	IHC
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

18kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Huang Y, et al. Proc Natl Acad Sci U S A. 2007, 104(10):4194-9.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck