ERG Rabbit Recombinant mAb

生物描述

特异性

ERG Rabbit Recombinant mAb detects endogenous level of total ERG.

背景

ERG is a member of the ETS gene family which is one of the largest families of transcriptional regulators consisting of at least 27 members, subdivided into 5 subfamilies. ERG consists of 17 exons and is transcribed to generate several alternately spliced forms. At least five splice variants are translated into proteins: ERG-1 (p41), ERG-2 (p52), ERG-3 (p55), ERG-4 (p49) and ERG-5 (p38) by a combination of alternative mRNA splicing and/or use of alternative polyadenlyation sites. ERG has been shown to regulate the normal platelet development, stem-cell function, definitive hematopoiesis and the normal megakaryopoiesis. ERG has also been shown to interface with genes linked to inflammation and DNA damage repair pathways.

使用信息

抗体应用	WB, IHC, IF,ELISA,ELISA
稀释比例	WB IHC IF 1:1000 1:50 1:50
反应性	Human Mouse Rat
MW (kDa)	55kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Taduru L Sreenath, et al. J Carcinog. 2011, 10: 37.

Application Data

WB

IHC

IF