FASN Rabbit Recombinant mAb

生物描述

特异性

FASN Rabbit Recombinant mAb detects endogenous level of total FASN.

背景

In the cytosol of animal cells, the reactions involved in fatty acid synthesis are catalyzed by a multifunctional FASN poly peptide--fatty acid synthase (FASN) in which substrates are handed from one functional domain to the next. FASN plays an essential role during embryo genesis and a key role in energy homeostasis in adult animals. FASN functions normally in the liver to make lipids for export to metabolically active tissues or storage in adipose tissue. On the contrary, FASN is minimally expressed in most other normal human tissues because they appear to use preferentially circulating fatty acids for the synthesis of new structural lipids.

使用信息

抗体应用	WB, IF,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	273kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Asturias FJ, et al. Nat Struct Mol Biol. 2005, 12(3):225-32. [2] Lupu R, et al. Endocrinology. 2006, 147(9):4056-66.

Application Data

WB

IF