FUBP1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	FUBP1 Rabbit Recombinant mAb detects endogenous level of total FUBP1.
背景	The far upstream element (FUSE)-binding protein 1 (FUBP1) is a transactivator of human c-myc proto-oncogene transcription, with important roles in carcinogenesis. FUBP1 is composed of three functional domains: a repression amino-terminal domain, a DNA-binding central domain, and a transactivation carboxyl-terminal domain. FUBP1 is broadly expressed in a wide variety of tissues and cells with a distinct spatial temporal profile where it influences a number of cellular processes, including differentiation, cell proliferation, apoptosis, or cell death through the effects of transcription, mRNA stability, and translation.

特异性

FUBP1 Rabbit Recombinant mAb detects endogenous level of total FUBP1.

背景

The far upstream element (FUSE)-binding protein 1 (FUBP1) is a transactivator of human c-myc proto-oncogene transcription, with important roles in carcinogenesis. FUBP1 is composed of three functional domains: a repression amino-terminal domain, a DNA-binding central domain, and a transactivation carboxyl-terminal domain. FUBP1 is broadly expressed in a wide variety of tissues and cells with a distinct spatial temporal profile where it influences a number of cellular processes, including differentiation, cell proliferation, apoptosis, or cell death through the effects of transcription, mRNA stability, and translation.

使用信息

抗体应用

WB, IHC, IF,ELISA,ELISA

稀释比例

WB	IHC	IF
1:1000	1:50	1:50

反应性

Human Mouse Rat

MW (kDa)

74kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Junyao Duan, et al. PLoS One. 2017, 12(1): e0169852.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck

IF

Validated by Selleck