生物描述

特异性

GSTO1 Rabbit Recombinant mAb detects endogenous levels of total GSTO1

背景

Glutathione S-transferases (GSTs) are a diverse family of cytosolic, mitochondrial and microsomal enzymes that are primarily involved in phase II metabolism. In addition to xenobiotic detoxification through glutathione conjugation, GSTs also play a key role in the synthesis and metabolism of endogenous compounds, redox homeostasis and cellular signaling. In humans, two GSTO isozymes GSTO1 and GSTO2 have been identified. They share 64% sequence identity and differ in their catalytic activities. GSTO1 catalyzes S-phenacyl glutathione reduction and monomethylarsonate (V) reduction, while GSTO2 has a prominent dehydroascorbate reductase activity.

使用信息

抗体应用	WB, IHC,ELISA,ELISA
稀释比例	WB IHC 1:1000 1:50
反应性	Human Rat
MW (kDa)	28kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Ramkumar K, et al. Nat Commun. 2016,5;7:13084.

Application Data

WB

IHC