生物描述

特异性

Golgin 97 Rabbit Recombinant mAb detects endogenous levels of total Golgin 97.

背景

Golgin-97 is a tethering factor in the trans-Golgi network (TGN) and is crucial for vesicular trafficking and maintaining cell polarity. Golgin-97 act as scaffold molecules and is recruited onto the TGN by interacting with Arf-like protein 1 (Arl1), an Arf small GTPase family member in the Ras superfamily, to establish a molecular platform required for numerous distinct processes of vesicle transport. It can also function as a tumor suppressor suppressing NF-κB signaling as well as cancer cell invasiveness. Although golgin-97 does not possess a transmembrane domain, its transmembrane localization inside the virion could be explained either by its potential lipid modification, possibly induced by virus, or by its interactions with viral membrane proteins.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human
MW (kDa)	97kDa
抗体类型
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Hsu RM, et al. Cell Commun Signal. 2018, 16(1):19. [2] Dina Alzhanova, et al. J Virol. 2006, 80(23): 11520–11527.

Application Data

WB

IF