Hexokinase 1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Hexokinase 1 Rabbit Recombinant mAb detects endogenous level of total Hexokinase 1.
背景	The first step in glucose metabolism is conversion of glucose to glucose 6-phosphate (G-6-P) by hexokinases (HKs), a family with 4 isoforms. The two most common isoforms, HKI and HKII, have overlapping tissue expression, but different subcellular distributions, with HKI associated mainly with mitochondria and HKII associated with both mitochondrial and cytoplasmic compartments. HKI is ubiquitous in most tissues but especially in brain and red blood cells, where glycolysis plays a critical role in energy production.

特异性

Hexokinase 1 Rabbit Recombinant mAb detects endogenous level of total Hexokinase 1.

背景

The first step in glucose metabolism is conversion of glucose to glucose 6-phosphate (G-6-P) by hexokinases (HKs), a family with 4 isoforms. The two most common isoforms, HKI and HKII, have overlapping tissue expression, but different subcellular distributions, with HKI associated mainly with mitochondria and HKII associated with both mitochondrial and cytoplasmic compartments. HKI is ubiquitous in most tissues but especially in brain and red blood cells, where glycolysis plays a critical role in energy production.

使用信息

抗体应用

WB, IF,ELISA,ELISA

稀释比例

WB	IF
1:1000	1:50

反应性

Human Mouse Rat

MW (kDa)

102kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] John S, et al. PLoS One. 2011, 6(3):e17674.

Application Data

WB

Validated by Selleck

IF

Validated by Selleck