Datasheet

生物描述

特异性	HBG1/2 Rabbit Recombinant mAb detects endogenous levels of total HBG1/2.
背景	The β-globin gene cluster of mammals contains a set of developmentally regulated genes that are arranged in their temporal order of expression. The ε-, γ-, and η-globin genes (HBE, HBG, and HBH, respectively) are expressed in embryonic erythroid cells and are descended from an ancestral HBE gene. The δ- and β-globin genes (HBD and HBB, respectively) are expressed in fetal and adult erythroid cells and are descended from an ancestral HBB gene. The γ-globin genes (HBG1 and HBG2) are active during fetal growth and are normally expressed in the fetal liver, spleen and bone marrow. The combination of two γ-globin chains and two α-globin chains forms fetal haemoglobin (HbF), which is the main oxygen transport protein in the human fetus.

特异性

HBG1/2 Rabbit Recombinant mAb detects endogenous levels of total HBG1/2.

背景

The β-globin gene cluster of mammals contains a set of developmentally regulated genes that are arranged in their temporal order of expression. The ε-, γ-, and η-globin genes (HBE, HBG, and HBH, respectively) are expressed in embryonic erythroid cells and are descended from an ancestral HBE gene. The δ- and β-globin genes (HBD and HBB, respectively) are expressed in fetal and adult erythroid cells and are descended from an ancestral HBB gene. The γ-globin genes (HBG1 and HBG2) are active during fetal growth and are normally expressed in the fetal liver, spleen and bone marrow. The combination of two γ-globin chains and two α-globin chains forms fetal haemoglobin (HbF), which is the main oxygen transport protein in the human fetus.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

12kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Opazo JC, et al. Proc Natl Acad Sci U S A. 2008, 105(35):12950-5.

Application Data

WB

Validated by Selleck