Histone H3 (mono methyl K36) Rabbit Recombinant mAb Datasheet

生物描述

特异性	Histone H3 (mono methyl K36) Rabbit Recombinant mAb detects endogenous level of total Histone H3 (mono methyl K36).
背景	Histone methylation acts as an epigenetic regulator of chromatin activity through the modification of arginine and lysine residues on histones H3 and H4. In the case of lysine, this includes the formation of mono-, di-, or trimethyl groups, each of which is presumed to represent a distinct functional state at the cellular level. Numerous HMTases have recently been characterized and are thought to catalyze the addition of methyl groups onto the amino terminal tails of histones H3 (K4, K9, K27, K36) and H4 (K20). Histone H3 K36 methylation is found in a broad range of distinct eukaryotes and is highly conserved. K36 methylation may have a broad range of activities in chromatin in addition to a conserved role with the transcribing polymerase.

特异性

Histone H3 (mono methyl K36) Rabbit Recombinant mAb detects endogenous level of total Histone H3 (mono methyl K36).

背景

Histone methylation acts as an epigenetic regulator of chromatin activity through the modification of arginine and lysine residues on histones H3 and H4. In the case of lysine, this includes the formation of mono-, di-, or trimethyl groups, each of which is presumed to represent a distinct functional state at the cellular level. Numerous HMTases have recently been characterized and are thought to catalyze the addition of methyl groups onto the amino terminal tails of histones H3 (K4, K9, K27, K36) and H4 (K20). Histone H3 K36 methylation is found in a broad range of distinct eukaryotes and is highly conserved. K36 methylation may have a broad range of activities in chromatin in addition to a conserved role with the transcribing polymerase.

使用信息

抗体应用

IF,ELISA,ELISA

稀释比例

IF

1:50

反应性

Human Mouse

MW (kDa)

15kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

IF

Validated by Selleck