hnRNP C1/C2 Rabbit Recombinant mAb

生物描述

特异性

hnRNP C1/C2 Rabbit Recombinant mAb detects endogenous level of total hnRNP C1/C2.

背景

Heterogeneous nuclear ribonucleoproteins (hnRNPs) comprise a family of RNA-binding proteins. The complexity and diversity associated with the hnRNPs render them multifunctional, involved not only in processing heterogeneous nuclear RNAs (hnRNAs) into mature mRNAs, but also acting as trans-factors in regulating gene expression. The hnRNP C1 and C2 proteins are among the most abundant proteins in the nucleus, and as ubiquitous components of RNP complexes, they have been implicated in many aspects of mRNA biogenesis. C1 and C2 proteins form stable heterotetramers that bind cooperatively to RNA and contain both an RNA recognition motif (RRM) and a unique bZIP-like RNA binding domain. hnRNP C is not required for cell viability.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	40kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Arindam Chaudhury, et al. RNA. 2010, 16(8): 1449-1462. [2] Williamson DJ, et al. Mol Cell Biol. 2000, 20(11):4094-105.

Application Data

WB

IF