HOXB9 Rabbit Recombinant mAb Datasheet

生物描述

特异性	HOXB9 Rabbit Recombinant mAb detects endogenous level of total HOXB9.
背景	HoxB9, a member of the homeobox-containing (HOX) transcriptional factor family, palys an important role in embryonic development and cancer progression. HOXB9 is reported to be frequently overexpressed in invasive human breast cancer, and promotes epithelial to mesenchymal transition (EMT). However, decreased expression of HOXB9 showed poor overall survival in colon adenocarcinoma, pancreatic ductal adenocarcinoma or gastric carcinoma patients, displaying an opposite role in cancer progression. HOXB9 is also a direct transcriptional target of the Wnt/TCF4 pathway in lung cancer.

特异性

HOXB9 Rabbit Recombinant mAb detects endogenous level of total HOXB9.

背景

HoxB9, a member of the homeobox-containing (HOX) transcriptional factor family, palys an important role in embryonic development and cancer progression. HOXB9 is reported to be frequently overexpressed in invasive human breast cancer, and promotes epithelial to mesenchymal transition (EMT). However, decreased expression of HOXB9 showed poor overall survival in colon adenocarcinoma, pancreatic ductal adenocarcinoma or gastric carcinoma patients, displaying an opposite role in cancer progression. HOXB9 is also a direct transcriptional target of the Wnt/TCF4 pathway in lung cancer.

使用信息

抗体应用

WB ,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

28kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Wan J, et al. Nucleic Acids Res. 2016, 44(22):10662-10675.

Application Data

WB

Validated by Selleck