HSPA2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	HSPA2 Rabbit Recombinant mAb detects endogenous level of total HSPA2.
背景	HSPA2 is a member of the HSP70 family of heat shock genes. Rodent HspA2 genes encode a molecular chaperone essential for dissociation of synaptonemal complexes, progression of meiosis and male fertility. Human HSPA2 gene is highly expressed in spermatids and tails of mature spermatozoa, suggesting its involvement in late stages of spermatid maturation. Relatively high levels of HSPA2 transcripts were found in various human non-testicular tissues, but the corresponding protein was essentially undetectable. In contrast to normal tissues, a significant expression of the HSPA2 protein was found in various human cancer cell lines and primary non-small-cell lung cancer tissues.

特异性

HSPA2 Rabbit Recombinant mAb detects endogenous level of total HSPA2.

背景

HSPA2 is a member of the HSP70 family of heat shock genes. Rodent HspA2 genes encode a molecular chaperone essential for dissociation of synaptonemal complexes, progression of meiosis and male fertility. Human HSPA2 gene is highly expressed in spermatids and tails of mature spermatozoa, suggesting its involvement in late stages of spermatid maturation. Relatively high levels of HSPA2 transcripts were found in various human non-testicular tissues, but the corresponding protein was essentially undetectable. In contrast to normal tissues, a significant expression of the HSPA2 protein was found in various human cancer cell lines and primary non-small-cell lung cancer tissues.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

70kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck