Id1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Id1 Rabbit Recombinant mAb detects endogenous level of total Id1.
背景	Id-1 (Inhibitor of differentiation/DNA binding) is a member of the helix-loop-helix protein family expressed in actively proliferating cells. It regulates gene transcription by heterodimerization with the basic helix-loop-helix transcription factors and therefore inhibits them from DNA binding and transactivation of their target genes. Id-1 has also been implicated as an oncogene which may play role in the tumorigenesis of a wide range of cancers. It also regulates events such as cellular senescence, cell growth, and cellular survival.

特异性

Id1 Rabbit Recombinant mAb detects endogenous level of total Id1.

背景

Id-1 (Inhibitor of differentiation/DNA binding) is a member of the helix-loop-helix protein family expressed in actively proliferating cells. It regulates gene transcription by heterodimerization with the basic helix-loop-helix transcription factors and therefore inhibits them from DNA binding and transactivation of their target genes. Id-1 has also been implicated as an oncogene which may play role in the tumorigenesis of a wide range of cancers. It also regulates events such as cellular senescence, cell growth, and cellular survival.

使用信息

抗体应用

WB, IHC, IF,ELISA,ELISA

稀释比例

WB	IHC	IF
1:1000	1:50	1:50

反应性

Human Mouse Rat

MW (kDa)

22kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Ling MT, et al. Differentiation. 2006, 74(9-10):481-7.

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck

IF

Validated by Selleck