全国免费电话:400-668-6834 -- 仅限中国地区 -- |
在线订购:QQ: 4006686834 电话订购:021-68591985 邮件订购:info@selleck.cn 我们也提供销售人员上门服务 |
技术支持电话:400-168-6834 我们将于一个工作日与您联系 |
目录号:A5887
特异性 | iNOS Rabbit Recombinant mAb detects endogenous levels of total iNOS. |
---|---|
背景 | Nitric oxide synthases (NOS) can be categorised into calcium dependent constitutive isoforms (endothelial NOS (eNOS) and neuronal NOS (nNOS)) and the calcium independent inducible isoform (iNOS), which is produced by a variety of mammalian cells as a result of cytokine and/or bacterial endotoxin stimulation. eNOS and nNOS only produce nanomolar concentrations of NO for seconds or minutes when activated. However, iNOS the inducible isoform generates higher amounts of NO, in the micromolar range and for longer intervals such as for hours or days. Thus, the expression levels of iNOS in tissues is a measure of NO generated in that tissue or its surrounding environment. iNOS overexpression produces pro-tumor or anti-tumor effects on tumor growth, depending on the tumor microenvironment and the tumor type in animal models. |
抗体应用 | wb,ELISA,ELISA | ||
---|---|---|---|
稀释比例 |
|
||
反应性 | Human Mouse | ||
MW (kDa) | 131kDa | ||
抗体类型 | |||
储存液配方 | 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide. | ||
储存条件 (自收到货起) |
Store at –20°C. |
|
WB
Validated by Selleck