IRF2 Rabbit Recombinant mAb Datasheet

生物描述

特异性	IRF2 Rabbit Recombinant mAb detects endogenous level of total IRF2.
背景	Interferon regulatory factor 2 (IRF2) is a member of a family of transcriptional factors involved in the modulation of IFN-induced immune responses to viral infection. It is a transcription repressor that is induced by IFNγ and acts as an antagonist to IRF1 to block the IFNγ-mediated pathway. IRF2 has been suggested to play a role in negative control of basophil expansion, which is critical for the regulation of Th1/Th2 balance. IRF2 may be an important candidate gene for Atopic dermatitis and eczema herpeticum.

特异性

IRF2 Rabbit Recombinant mAb detects endogenous level of total IRF2.

背景

Interferon regulatory factor 2 (IRF2) is a member of a family of transcriptional factors involved in the modulation of IFN-induced immune responses to viral infection. It is a transcription repressor that is induced by IFNγ and acts as an antagonist to IRF1 to block the IFNγ-mediated pathway. IRF2 has been suggested to play a role in negative control of basophil expansion, which is critical for the regulation of Th1/Th2 balance. IRF2 may be an important candidate gene for Atopic dermatitis and eczema herpeticum.

使用信息

抗体应用

WB, IF,ELISA,ELISA

稀释比例

WB	IF
1:1000	1:50

反应性

Human Mouse

MW (kDa)

50kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Gao PS, et al. J Invest Dermatol. 2012, 132(3 Pt 1):650-7.

Application Data

WB

Validated by Selleck

IF

Validated by Selleck