Islet1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	Islet1 Rabbit Recombinant mAb detects endogenous level of total Islet1.
背景	Islet1 (Isl1) is a LIM homedomain protein that plays a pivotal role in cardiac progenitors of the second heart field. Its expression is often used as a marker of the second myocardial lineage during mammalian cardiogenesis. Isl1 also expresses in embryonic motoneurons, a variety of cell lineages of pancreatic endocrine origin during embryogenesis, as well as in normal adult islet cells. Since Isl1 expression delineates undifferentiated and differentiated progenitor states, it represents an excellent lineage tracer for cardiac mesodermal cells during embryogenesis.

特异性

Islet1 Rabbit Recombinant mAb detects endogenous level of total Islet1.

背景

Islet1 (Isl1) is a LIM homedomain protein that plays a pivotal role in cardiac progenitors of the second heart field. Its expression is often used as a marker of the second myocardial lineage during mammalian cardiogenesis. Isl1 also expresses in embryonic motoneurons, a variety of cell lineages of pancreatic endocrine origin during embryogenesis, as well as in normal adult islet cells. Since Isl1 expression delineates undifferentiated and differentiated progenitor states, it represents an excellent lineage tracer for cardiac mesodermal cells during embryogenesis.

使用信息

抗体应用

WB, IF,ELISA,ELISA

稀释比例

WB	IF
1:1000	1:50

反应性

Human Mouse

MW (kDa)

39kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Laugwitz KL, et al. Development. 2008, 135(2):193-205.

Application Data

WB

Validated by Selleck

IF

Validated by Selleck