KAT9/Elp3 Rabbit Recombinant mAb

生物描述

特异性

KAT9/Elp3 Rabbit Recombinant mAb detects endogenous level of total KAT9/Elp3.

背景

The highly conserved KAT, KAT9 (formerly Elongator protein 3, Elp3) is the catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. In mammals, ELP3 is important for paternal DNA demethylation after fertilization. ELP3 is potentially involved in cellular redox homeostasis by mediating the acetylation of glucose-6-phosphate dehydrogenase. Besides, ELP3 may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4.

使用信息

抗体应用	WB, IF,ELISA,ELISA
稀释比例	WB IF 1:1000 1:50
反应性	Human Mouse Rat
MW (kDa)	62kDa
抗体类型	Rabbit
储存液配方	10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.
储存条件 (自收到货起)	Store at –20°C.

文献参考

[1] Kim JH, et al. Proc Natl Acad Sci U S A. 2002, 99(3):1241-6. [2] Strausberg RL, et al. Proc Natl Acad Sci U S A. 2002, 99(26):16899-903.

Application Data

WB

IF