Lactoferrin Rabbit Recombinant mAb Datasheet

生物描述

特异性	Lactoferrin Rabbit Recombinant mAb detects endogenous level of total Lactoferrin.
背景	Lactoferrin (LF) is an 80 kDa iron-binding glycoprotein of the transferrin family that is expressed in most biological fluids and is a major component of the mammalian innate immune system. Its protective effects range from direct antimicrobial activities against a large panel of microorganisms, including bacteria, viruses, fungi and parasites, to anti-inflammatory and anticancer activities. It is considered a key component in the host’s first line of defence, as it has the ability to respond to a variety of physiological and environmental changes. LF plays a key role in maintaining cellular iron levels in the body. It is a modulator of the innate and acquired immune systems. In addition to inducing systemic immunity, LF can promote skin immunity and inhibit allergic responses. It induces the immune system against skin allergens, causing dose-dependent inhibition of Langerhans cellmigration and the accumulation of dendritic cells in lymph nodes.

特异性

Lactoferrin Rabbit Recombinant mAb detects endogenous level of total Lactoferrin.

背景

Lactoferrin (LF) is an 80 kDa iron-binding glycoprotein of the transferrin family that is expressed in most biological fluids and is a major component of the mammalian innate immune system. Its protective effects range from direct antimicrobial activities against a large panel of microorganisms, including bacteria, viruses, fungi and parasites, to anti-inflammatory and anticancer activities. It is considered a key component in the host’s first line of defence, as it has the ability to respond to a variety of physiological and environmental changes. LF plays a key role in maintaining cellular iron levels in the body. It is a modulator of the innate and acquired immune systems. In addition to inducing systemic immunity, LF can promote skin immunity and inhibit allergic responses. It induces the immune system against skin allergens, causing dose-dependent inhibition of Langerhans cellmigration and the accumulation of dendritic cells in lymph nodes.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

78kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] González-Chávez SA, et al. Int J Antimicrob Agents. 2009, 33(4):301.e1-8.

Application Data

WB

Validated by Selleck