LYVE1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	LYVE1 Rabbit Recombinant mAb detects endogenous level of total LYVE1.
背景	Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1), also known as extracellular link domain containing 1 (XLKD1) is a Link domain-containing hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. HA is the major glyscosaminoglycan in extracellular matrix, highly enriched in connective and epithelial tissues. The binding of HA to LYVE-1 activates intracellular signalling, to promote lymphangiogenesis in vitro. LYVE1 is expressed in the lymphatic endothelium, blood sinus endothelium, and certain macrophage lineages and is a novel marker for the reticulo-endothelial system (RES).

特异性

LYVE1 Rabbit Recombinant mAb detects endogenous level of total LYVE1.

背景

Lymphatic vessel endothelial hyaluronan receptor 1 (LYVE1), also known as extracellular link domain containing 1 (XLKD1) is a Link domain-containing hyaladherin, a protein capable of binding to hyaluronic acid (HA), homologous to CD44, the main HA receptor. HA is the major glyscosaminoglycan in extracellular matrix, highly enriched in connective and epithelial tissues. The binding of HA to LYVE-1 activates intracellular signalling, to promote lymphangiogenesis in vitro. LYVE1 is expressed in the lymphatic endothelium, blood sinus endothelium, and certain macrophage lineages and is a novel marker for the reticulo-endothelial system (RES).

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

35kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck