Datasheet

生物描述

特异性	MAPKAP Kinase 2 Rabbit Recombinant mAb detects endogenous levels of total MAPKAP Kinase 2
背景	Mitogen activated protein kinase-activated protein kinase 2 (MAPKAP kinase 2 or MK2) is a serine threonine kinase directly phosphorylated and activated by the p38 mitogen activated protein kinase (MAPK)/reactivating kinase. MK2 is a direct substrate for p38. The p38 MAPKs regulate a number of environmental stress responses including actin microfilament dynamics, levels of intracellular reactive oxygen species (ROS), apoptosis, and the biosynthesis of several proin£ammatory cytokines including TNF-K, IL1, and IL6.

特异性

MAPKAP Kinase 2 Rabbit Recombinant mAb detects endogenous levels of total MAPKAP Kinase 2

背景

Mitogen activated protein kinase-activated protein kinase 2 (MAPKAP kinase 2 or MK2) is a serine threonine kinase directly phosphorylated and activated by the p38 mitogen activated protein kinase (MAPK)/reactivating kinase. MK2 is a direct substrate for p38. The p38 MAPKs regulate a number of environmental stress responses including actin microfilament dynamics, levels of intracellular reactive oxygen species (ROS), apoptosis, and the biosynthesis of several proin£ammatory cytokines including TNF-K, IL1, and IL6.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

46kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Yannoni YM, et al. FEBS Lett. 2004,23;564(1-2):205-11.

Application Data

WB

Validated by Selleck