MEK1 Rabbit Recombinant mAb Datasheet

生物描述

特异性	MEK1 Rabbit Recombinant mAb detects endogenous levels of total MEK1.
背景	MEK1 (MAP2K1) is one of the subtypes of MEK (MAPKK) which is a dual specificity protein kinase. MEK1 and MEK2 are two main subtypes of MEK. Both MEK1 and MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade.

特异性

MEK1 Rabbit Recombinant mAb detects endogenous levels of total MEK1.

背景

MEK1 (MAP2K1) is one of the subtypes of MEK (MAPKK) which is a dual specificity protein kinase. MEK1 and MEK2 are two main subtypes of MEK. Both MEK1 and MEK2 function specifically in the MAPK/ERK cascade, and catalyze the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in the extracellular signal-regulated kinases MAPK3/ERK1 and MAPK1/ERK2, leading to their activation and further transduction of the signal within the MAPK/ERK cascade.

使用信息

抗体应用

WB, IF, IHC,ELISA,ELISA

稀释比例

WB	IHC	IF
1:1000	1:50	1:50

反应性

Human Mouse Rat Bovine Dog

MW (kDa)

45kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck

IHC

Validated by Selleck

IF

Validated by Selleck