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别名 | MitoQ10 mesylate, Mitoubiquinone mesylate | 储存条件 (自收到货起) |
2年 -20°C 液体 | ||||
化学式 | C38H47O7PS |
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分子量 | 678.81 | CAS号 | 845959-50-4 | ||||
Solubility (25°C)* | 体外 | DMSO | 50 mg/mL (73.65 mM) | ||||
Water | 9 mg/mL (13.25 mM) | ||||||
Ethanol | Insoluble | ||||||
体内(现配现用) |
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Selleck tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
产品描述 | MitoQ (Mitoquinone) mesylate是一种基于TPP的线粒体mitochondria靶向抗氧化剂,可阻断H2O2诱导的细胞内 ROS 反应并防止氧化损伤。该产品呈胶状。 | ||
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靶点 |
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Local production of reactive oxygen species drives vincristine-induced axon degeneration [ Cell Death Dis, 2023, 14(12):807] | PubMed: 38065950 |
O-GlcNAcylation Is Required for the Survival of Cerebellar Purkinje Cells by Inhibiting ROS Generation [ Antioxidants (Basel), 2023, 12(4)806] | PubMed: 37107182 |
Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis [ iScience, 2023, 26(9):107647] | PubMed: 37694150 |
MitoQ Protects Ovarian Organoids against Oxidative Stress during Oogenesis and Folliculogenesis In Vitro [ Int J Mol Sci, 2023, 24(2)924] | PubMed: 36674435 |
Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling [ Immunity, 2022, S1074-7613(22)00280-1] | PubMed: 35835107 |
Very-low-density lipoprotein receptor-enhanced lipid metabolism in pancreatic stellate cells promotes pancreatic fibrosis [ Immunity, 2022, 55(7):1185-1199.e8] | PubMed: 35738281 |
HDAC class I inhibitor domatinostat sensitizes pancreatic cancer to chemotherapy by targeting cancer stem cell compartment via FOXM1 modulation [ J Exp Clin Cancer Res, 2022, 41(1):83] | PubMed: 35241126 |
Benchmarking AlphaFold-enabled molecular docking predictions for antibiotic discovery [ Mol Syst Biol, 2022, 18(9):e11081] | PubMed: 36065847 |
PARP-inhibition reprograms macrophages toward an anti-tumor phenotype [ Cell Rep, 2022, 41-2:111462] | PubMed: 36223740 |
Loss of legumain induces premature senescence and mediates aging-related renal fibrosis [ Aging Cell, 2022, 21(3):e13574] | PubMed: 35195326 |
特定的存储和包装每个产品的信息在产品说明书上都有注明。大多数Selleck产品,在推荐的条件下存储可稳定保存两年。产品有时建议的储存温度不同,大多数建议储存在-20°C,抑制剂属于化学试剂,可在常温下运输储存两周左右。即使如此,我们保证产品的出货量将保持产品质量的条件下,一般都会放入冰袋。望阁下收到产品后,请按照产品数据表建议适当存储。
如果需要长期保存,请于零下二十度低温保存。禁止用于人体及治疗!
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