Datasheet

生物描述

特异性	mSin3A Rabbit Recombinant mAb detects endogenous levels of total mSin3A.
背景	mSin3A is a core component of a large multiprotein corepressor complex with associated histone deacetylase (HDAC) enzymatic activity. It functions as a platform that mediates the association of histone deacetylase (HDAC) enzymes and other chromatin-modifying activities with a large number of DNA-binding transcriptional repressors. Physical interactions of mSin3A with many sequence-specific transcription factors has linked the mSin3A corepressor complex to the regulation of diverse signaling pathways and associated biological processes. mSin3A is essential for early embryonic development and for cellular proliferation and survival.

特异性

mSin3A Rabbit Recombinant mAb detects endogenous levels of total mSin3A.

背景

mSin3A is a core component of a large multiprotein corepressor complex with associated histone deacetylase (HDAC) enzymatic activity. It functions as a platform that mediates the association of histone deacetylase (HDAC) enzymes and other chromatin-modifying activities with a large number of DNA-binding transcriptional repressors. Physical interactions of mSin3A with many sequence-specific transcription factors has linked the mSin3A corepressor complex to the regulation of diverse signaling pathways and associated biological processes. mSin3A is essential for early embryonic development and for cellular proliferation and survival.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human Mouse Rat

MW (kDa)

150kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

Application Data

WB

Validated by Selleck