NEFM Rabbit Recombinant mAb Datasheet

生物描述

特异性	NEFM Rabbit Recombinant mAb detects endogenous level of total NEFM.
背景	NEFM encodes one of the subunits forming the neurofilament, the type IV intermediate filament of mature neurons, one of the most abundant proteins in the nervous system. Besides its structural role in the neuronal cytoskeleton, NEFM has specialized biological functions in the synaptic densities where it colocalizes with D1R and regulates its agonist-induced desensitization. NEFM is a DR (dopamine receptor)-interacting protein. It interacts directly with the cytoplasmic loop of D1R.

特异性

NEFM Rabbit Recombinant mAb detects endogenous level of total NEFM.

背景

NEFM encodes one of the subunits forming the neurofilament, the type IV intermediate filament of mature neurons, one of the most abundant proteins in the nervous system. Besides its structural role in the neuronal cytoskeleton, NEFM has specialized biological functions in the synaptic densities where it colocalizes with D1R and regulates its agonist-induced desensitization. NEFM is a DR (dopamine receptor)-interacting protein. It interacts directly with the cytoplasmic loop of D1R.

使用信息

抗体应用

WB,ELISA,ELISA

稀释比例

WB

1:1000

反应性

Human

MW (kDa)

160kDa

抗体类型

Rabbit

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Maniero C, et al. Hypertension. 2017, 70(2):357-364.

Application Data

WB

Validated by Selleck