Datasheet

目录号：A5795

生物描述

特异性	NR5A2 Rabbit Recombinant mAb detects endogenous levels of total NR5A2.
背景	NR5A2 is an orphan nuclear hormone receptor that has diverse developmental and physiological functions. It is expressed in the inner cell mass of early mouse embryos and in the developing endoderm. NR5A2 is involved in the regulation of development, lipid metabolism and proliferation and is predominantly expressed in epithelial tissues. Tissue-specific deletion or inhibition of NR5A2 and associated intestinal glucocorticoid synthesis consequently results in increased susceptibility to the development of intestinal inflammatory disorders.

特异性

NR5A2 Rabbit Recombinant mAb detects endogenous levels of total NR5A2.

背景

NR5A2 is an orphan nuclear hormone receptor that has diverse developmental and physiological functions. It is expressed in the inner cell mass of early mouse embryos and in the developing endoderm. NR5A2 is involved in the regulation of development, lipid metabolism and proliferation and is predominantly expressed in epithelial tissues. Tissue-specific deletion or inhibition of NR5A2 and associated intestinal glucocorticoid synthesis consequently results in increased susceptibility to the development of intestinal inflammatory disorders.

使用信息

抗体应用

wb,ELISA,ELISA

稀释比例

1:1000

反应性

Human Mouse Rat

MW (kDa)

65kDa

抗体类型

储存液配方

10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 µg/ml BSA, 50% glycerol and less than 0.02% sodium azide.

储存条件
(自收到货起)

Store at –20°C.

文献参考

[1] Schwaderer J. et al. Cell Death Dis. 2017, 8(4):e2745.
[2] NR5A2: a central player in pancreas development. Development. 2014 141: e1603.

Application Data

Validated by Selleck